Single ventricle physiology

Oxygen metabolism

Oxygen delivery at the level of the tissues represents a continuous flux of oxygen molecules that dissociate from hemoglobin, into the plasma, through the water of the interstitial spaces, and into the mitochondrion down a concentration gradient.  The tissue PO2 is a volume-averaged concentration of oxygen molecules within the water of the interstitium.  

Simplified paradigm

Contribution of anatomy to saturation


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